Compile Data Set for Download or QSAR

Found 380 hits of ic50 data for polymerid = 50006302   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50614629 (BAY-293) Show SMILES CNCc1ccccc1-c1csc(c1)[C@@H](C)Nc1nc(C)nc2cc(OC)c(OC)cc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PDB UniChem	PDB	n/a	n/a	6.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair				3D Structure (crystal)
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50614625 (CHEMBL5290935) Show SMILES COc1cc2ncnc(NC(C)c3ccc(s3)-c3ccccc3CNCCO)c2cc1OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	8.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50590056 (CHEMBL5171547) Show SMILES [H][C@]12CN(CCN1c1cc3c(N[C@H](C)c4cccc(C(F)F)c4F)nc(C)nc3cc1OCC2)C(=O)[C@@H]1CCOC1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00986 BindingDB Entry DOI: 10.7270/Q2M61Q7G
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50590063 (CHEMBL5184087) Show SMILES [H][C@]12CN(CCOC)CCN1c1cc3c(N[C@H](C)c4cccc(C(F)F)c4F)nc(C)nc3cc1OCC2 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00986 BindingDB Entry DOI: 10.7270/Q2M61Q7G
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50590051 (CHEMBL5184590) Show SMILES [H][C@@]12COc3cc4nc(C)nc(N[C@H](C)c5cccc(C(F)F)c5F)c4cc3N1CCN(C2)C(=O)C1(CC1)C#N |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00986 BindingDB Entry DOI: 10.7270/Q2M61Q7G
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50590054 (CHEMBL5201901) Show SMILES [H][C@]12CN(CCN1c1cc3c(N[C@H](C)c4cccc(C(F)F)c4F)nc(C)nc3cc1OCC2)C(=O)C1COC1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00986 BindingDB Entry DOI: 10.7270/Q2M61Q7G
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50590061 (CHEMBL5196432) Show SMILES [H][C@]12CN(CC(F)(F)F)CCN1c1cc3c(N[C@H](C)c4cccc(C(F)F)c4F)nc(C)nc3cc1OCC2 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00986 BindingDB Entry DOI: 10.7270/Q2M61Q7G
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50614624 (CHEMBL5280958) Show SMILES COc1cc2ncnc(NC(C)c3cc(cs3)-c3ccccc3CNCCO)c2cc1OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50590049 (CHEMBL5209105) Show SMILES [H][C@]12CN(CCN1c1cc3c(N[C@H](C)c4cccc(C(F)F)c4F)nc(C)nc3cc1OCC2)C(=O)C1(CC1)C#N |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00986 BindingDB Entry DOI: 10.7270/Q2M61Q7G
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50614623 (CHEMBL5286756) Show SMILES CNCc1ccccc1-c1csc(c1)C(C)Nc1ncnc2cc(OC)c(OC)cc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50614626 (CHEMBL5278156) Show SMILES CNCc1ccccc1-c1csc(c1)C(C)Nc1nc(C)nc2cc3OCCOc3cc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50590064 (CHEMBL5195849) Show SMILES [H][C@]12CN(CC3COC3)CCN1c1cc3c(N[C@H](C)c4cccc(C(F)F)c4F)nc(C)nc3cc1OCC2 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00986 BindingDB Entry DOI: 10.7270/Q2M61Q7G
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50590059 (CHEMBL5201816) Show SMILES [H][C@]12CN(C)CCN1c1cc3c(N[C@H](C)c4cccc(C(F)F)c4F)nc(C)nc3cc1OCC2 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00986 BindingDB Entry DOI: 10.7270/Q2M61Q7G
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50590065 (CHEMBL5185398) Show SMILES [H][C@]12CN(CCN1c1cc3c(N[C@H](C)c4cccc(C(F)F)c4F)nc(C)nc3cc1OCC2)c1ccnn1C |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00986 BindingDB Entry DOI: 10.7270/Q2M61Q7G
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50590050 (CHEMBL5203150) Show SMILES C[C@@H](Nc1nc(C)nc2cc(O)c(O[C@H]3CCOC3)cc12)c1cc(N)cc(c1)C(F)(F)F |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00986 BindingDB Entry DOI: 10.7270/Q2M61Q7G
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50581659 (CHEMBL4519023 | US20230339952, Comparative Compoun...) Show SMILES COc1cc2nc(C)nc(N[C@H](C)c3cc(N)cc(c3)C(F)(F)F)c2cc1O[C@H]1CCOC1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SOS1-mediated proliferation of human DLD-1 cells assessed as proliferation incubated for 5 to 14 days by AlamarBlue based 3D proliferat...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01949 BindingDB Entry DOI: 10.7270/Q2154MXQ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50590057 (CHEMBL5183723) Show SMILES [H][C@]12CN(CCN1c1cc3c(N[C@H](C)c4cccc(C(F)F)c4F)nc(C)nc3cc1OCC2)C(=O)c1ccnn1C |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00986 BindingDB Entry DOI: 10.7270/Q2M61Q7G
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50614627 (CHEMBL5284477) Show SMILES CC(Nc1nc(C)nc2cc3OCCOc3cc12)c1cc(cs1)-c1ccccc1CNCCO Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50590053 (CHEMBL5170314) Show SMILES [H][C@]12CN(CCN1c1cc3c(N[C@H](C)c4cccc(C(F)F)c4F)nc(C)nc3cc1OCC2)C(=O)C(C)(C)C |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00986 BindingDB Entry DOI: 10.7270/Q2M61Q7G
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50590058 (CHEMBL5185573) Show SMILES [H][C@]12CN(CCN1c1cc3c(N[C@H](C)c4cccc(C(F)F)c4F)nc(C)nc3cc1OCC2)C(=O)c1cccnc1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00986 BindingDB Entry DOI: 10.7270/Q2M61Q7G
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50590066 (CHEMBL5193498) Show SMILES [H][C@]12CN(CCN1c1cc3c(N[C@H](C)c4cccc(C(F)F)c4F)nc(C)nc3cc1OCC2)[C@H]1CCOC1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00986 BindingDB Entry DOI: 10.7270/Q2M61Q7G
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50406167 (CHEMBL5275216) Show SMILES CON1CCN2Cc3[nH]c4ccccc4c3CC2C1 Show InChI InChI=1S/C15H19N3O/c1-19-18-7-6-17-10-15-13(8-11(17)9-18)12-4-2-3-5-14(12)16-15/h2-5,11,16H,6-10H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In vitro inhibitory effect of histamine H3 antagonist on the electrically evoked contractile response of isolated guinea pig jejunum segments.				Citation and Details
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50590062 (CHEMBL5208418) Show SMILES [H][C@]12CN(CC#N)CCN1c1cc3c(N[C@H](C)c4cccc(C(F)F)c4F)nc(C)nc3cc1OCC2 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00986 BindingDB Entry DOI: 10.7270/Q2M61Q7G
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50406154 (CHEMBL5280533) Show SMILES ClN1CCN2Cc3[nH]c4ccccc4c3CC2C1 Show InChI InChI=1S/C14H16ClN3/c15-18-6-5-17-9-14-12(7-10(17)8-18)11-3-1-2-4-13(11)16-14/h1-4,10,16H,5-9H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In vitro inhibitory effect of histamine H3 antagonist on the electrically evoked contractile response of isolated guinea pig jejunum segments.				Citation and Details
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50581659 (CHEMBL4519023 | US20230339952, Comparative Compoun...) Show SMILES COc1cc2nc(C)nc(N[C@H](C)c3cc(N)cc(c3)C(F)(F)F)c2cc1O[C@H]1CCOC1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB	n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In vitro inhibitory effect of histamine H3 antagonist on the electrically evoked contractile response of isolated guinea pig jejunum segments.				Citation and Details
					More data for this Ligand-Target Pair				3D Structure (crystal)
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50406153 (CHEMBL5290547) Show SMILES CCc1ccccc1NC(=O)CCN1CCN2Cc3[nH]c4ccccc4c3CC2C1 Show InChI InChI=1S/C25H30N4O/c1-2-18-7-3-5-9-22(18)27-25(30)11-12-28-13-14-29-17-24-21(15-19(29)16-28)20-8-4-6-10-23(20)26-24/h3-10,19,26H,2,11-17H2,1H3,(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In vitro inhibitory effect of histamine H3 antagonist on the electrically evoked contractile response of isolated guinea pig jejunum segments.				Citation and Details
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50406161 (CHEMBL5286601) Show SMILES [O-][N+](=O)N1CCN2Cc3[nH]c4ccccc4c3CC2C1 Show InChI InChI=1S/C14H16N4O2/c19-18(20)17-6-5-16-9-14-12(7-10(16)8-17)11-3-1-2-4-13(11)15-14/h1-4,10,15H,5-9H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In vitro inhibitory effect of histamine H3 antagonist on the electrically evoked contractile response of isolated guinea pig jejunum segments.				Citation and Details
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50590060 (CHEMBL5183879) Show SMILES [H][C@]12CN(CCN1c1cc3c(N[C@H](C)c4cccc(C(F)F)c4F)nc(C)nc3cc1OCC2)C(C)C |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00986 BindingDB Entry DOI: 10.7270/Q2M61Q7G
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50406169 (CHEMBL5269963) Show SMILES COc1ccccc1NC(=O)CCN1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C22H28N2O2/c1-26-21-10-6-5-9-20(21)23-22(25)13-16-24-14-11-19(12-15-24)17-18-7-3-2-4-8-18/h2-10,19H,11-17H2,1H3,(H,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem		n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In vitro inhibitory effect of histamine H3 antagonist on the electrically evoked contractile response of isolated guinea pig jejunum segments.				Citation and Details
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50590055 (CHEMBL5191638) Show SMILES [H][C@]12CN(CCN1c1cc3c(N[C@H](C)c4cccc(C(F)F)c4F)nc(C)nc3cc1OCC2)C(=O)OC1COC1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00986 BindingDB Entry DOI: 10.7270/Q2M61Q7G
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50406155 (CHEMBL5284292) Show SMILES Clc1ccccc1NC(=O)CCN1CCN2Cc3[nH]c4ccccc4c3CC2C1 Show InChI InChI=1S/C23H25ClN4O/c24-19-6-2-4-8-21(19)26-23(29)9-10-27-11-12-28-15-22-18(13-16(28)14-27)17-5-1-3-7-20(17)25-22/h1-8,16,25H,9-15H2,(H,26,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In vitro inhibitory effect of histamine H3 antagonist on the electrically evoked contractile response of isolated guinea pig jejunum segments.				Citation and Details
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50590052 (CHEMBL5181797) Show SMILES [H][C@]12CN(CCN1c1cc3c(N[C@H](C)c4cccc(C(F)F)c4F)nc(C)nc3cc1OCC2)C(N)=O |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00986 BindingDB Entry DOI: 10.7270/Q2M61Q7G
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50406151 (CHEMBL5266985) Show SMILES O=C(NCCN1CCC(Cc2ccccc2)CC1)c1ccccc1 Show InChI InChI=1S/C21H26N2O/c24-21(20-9-5-2-6-10-20)22-13-16-23-14-11-19(12-15-23)17-18-7-3-1-4-8-18/h1-10,19H,11-17H2,(H,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Anti-vasopressor activity at V1a receptor				Citation and Details
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50406168 (CHEMBL5267612) Show SMILES O=C(CCN1CCC(Cc2ccccc2)CC1)Nc1ccccc1 Show InChI InChI=1S/C21H26N2O/c24-21(22-20-9-5-2-6-10-20)13-16-23-14-11-19(12-15-23)17-18-7-3-1-4-8-18/h1-10,19H,11-17H2,(H,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	91	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In vitro inhibitory effect of histamine H3 antagonist on the electrically evoked contractile response of isolated guinea pig jejunum segments.				Citation and Details
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50406162 (CHEMBL5275839) Show SMILES Fc1ccccc1NC(=O)CCN1CCN2Cc3[nH]c4ccccc4c3CC2C1 Show InChI InChI=1S/C23H25FN4O/c24-19-6-2-4-8-21(19)26-23(29)9-10-27-11-12-28-15-22-18(13-16(28)14-27)17-5-1-3-7-20(17)25-22/h1-8,16,25H,9-15H2,(H,26,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	93	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In vitro inhibitory effect of histamine H3 antagonist on the electrically evoked contractile response of isolated guinea pig jejunum segments.				Citation and Details
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50406150 (CHEMBL5280431) Show SMILES NN1CCN2Cc3[nH]c4ccccc4c3CC2C1 Show InChI InChI=1S/C14H18N4/c15-18-6-5-17-9-14-12(7-10(17)8-18)11-3-1-2-4-13(11)16-14/h1-4,10,16H,5-9,15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	94	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antidiuretic activity at V2 receptor				Citation and Details
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50406166 (CHEMBL5274267) Show SMILES Ic1ccccc1C(=O)NCCN1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C20H24IN3O/c21-19-9-5-4-8-18(19)20(25)22-10-11-23-12-14-24(15-13-23)16-17-6-2-1-3-7-17/h1-9H,10-16H2,(H,22,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem		n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In vitro inhibitory effect of histamine H3 antagonist on the electrically evoked contractile response of isolated guinea pig jejunum segments.				Citation and Details
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50614628 (CHEMBL5287441) Show SMILES CNCc1ccccc1-c1csc(c1)C(C)Nc1ncnc2cc3OCCOc3cc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	97	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM602190 (1-(4-((R)-1-(2-fluoro-3-(difluoromethyl)phenyl)eth...) Show SMILES COc1nc2nc(C)nc(N[C@H](C)c3cccc(C(F)F)c3F)c2cc1C1(CC1)C#N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2WQ07Q7
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM602191 (US11648254, Compound 102) Show SMILES COc1nc2nc(C)nc(N[C@H](C)c3cccc(C(F)F)c3F)c2cc1C1CCS(=O)(=O)CC1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2WQ07Q7
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM602192 (BDBM602215 | US11648254, Compound 103) Show SMILES COc1nc2nc(C)nc(N[C@H](C)c3cccc(C(F)F)c3F)c2cc1N1CCN(C)CC1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2WQ07Q7
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM602193 (US11648254, Compound 104) Show SMILES C[C@@H](Nc1nc(C)nc2[nH]c(=O)c(cc12)C1CCN(CC1)C(=O)OC(C)(C)C)c1cccc(C(F)F)c1F |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2WQ07Q7
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM602194 (US11648254, Compound 105) Show SMILES CC(C)N1CCN(Cc2cc3c(N[C@H](C)c4cccc(C(F)F)c4F)nc(C)nc3nc2Cl)CC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2WQ07Q7
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM602195 (US11648254, Compound 106) Show SMILES C[C@@H](Nc1nc(C)nc2NC(Cl)C(=Cc12)S(=O)(=O)N1CCN(Cc2ccccc2)CC1)c1cccc(C(F)F)c1F |r,c:12| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2WQ07Q7
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM602196 (US11648254, Compound 107) Show SMILES COc1ccc(CNc2nnc(cc2C(N)=O)N2CCN(CC2)C(C)C)c(OC)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2WQ07Q7
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM602197 (US11648254, Compound 108) Show SMILES CC(C)N1CCN(CC1)c1cc2c(N[C@H](C)c3cccc(C(F)F)c3F)nc(C)nc2nn1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2WQ07Q7
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM602198 ((R)-N-(1-(3-(difluoromethyl)-2- fluorophenyl)ethyl...) Show SMILES COc1nc2nc(C)nc(N[C@H](C)c3cccc(C(F)F)c3F)c2cc1N1CCN(CC1)C(C)C |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2WQ07Q7
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM602199 ((R)-N-(1-(3-(difluoromethyl)-2- fluorophenyl)ethyl...) Show SMILES COc1nc2nc(C)nc(N[C@H](C)c3cccc(C(F)F)c3F)c2cc1N1CCNCC1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2WQ07Q7
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM602201 ((R)-N-(1-(3-(difluoromethyl)-2- fluorophenyl)ethyl...) Show SMILES COc1nc2nc(C)nc(N[C@H](C)c3cccc(C(F)F)c3F)c2cc1C1CCN(CC1)C(C)C |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2WQ07Q7
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM602204 ((R)-N-(1-(3-(difluoromethyl)-2- fluorophenyl)ethyl...) Show SMILES COc1nc2nc(C)nc(N[C@H](C)c3cccc(C(F)F)c3F)c2cc1C1CCN(C)CC1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2WQ07Q7
					More data for this Ligand-Target Pair

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